Ugh sorry, image didn't upload with the question. This is the image I'm referencing in the post^

does she show any signs of MBD? I had a crestie with MBD whose eyes were very caddywompus. one was larger than the other but always had a smaller pupil.

Is it possible the focus area of the photo is creating an illusion?

Does the pupil react to light?

Sometimes Cresteds will have one eye normal and one eye smaller, or not as "full" as the normal eye.  A lot of times smaller eye will look a little bit darker.  In the smaller, darker eye the pupil will frequently not react to light, and the geckos seem to be blind on that side.  I had one gecko like this.  It can be something that is present from birth, or sometimes it can be the result of an injury.  The geckos do just fine, eating, climbing, etc.  Mine was a little bit more clumsy than the others.  It doesn't seem that this is usually reversible/fixable.

Also, sometimes one eye is normal, and the other eye is abnormally full or big.  That seems to be caused by a blocked duct that doesn't allow the intraocular fluid to drain, so the eye just keeps bulging with fluid.  Some people take them to the vet, and the vet uses a needle to suck out some of the excess fluid, but it builds back up again.  As far as I've read, none of these geckos have ever had their eye burst from too much fluid, even though their eyes look like bubbles ready to pop.  I haven't had a gecko like this, so I don't have much first had experience with it.  Just what I've read. 

Guessing from the picture I'd think that she had some sort of injury to the eye, and may be blind in it.  The pupils in the picture don't appear to be dilated similarly, and the smaller "deflated" one looks a tad bit darker.  But perhaps it's just the lighting of the picture.  She's a cutie pie for sure though!

Other than the goofy eyes she seems totally healthy (she's my first gecko, but she was bred by a friend of mine [Hi Abby! :P] who wouln't have let me take her if she were showing anything obvious). 

The smaller eye does seem to be darker, I'll have to check on how it reacts to light - in that image there is a bright light on the same side as the smaller eye, so I assumed that's why the pupil is so thin on that side.

Thanks everyone! (not closing this yet, I want to see if there are any other possibilities)

 One of the baby leos we produced last year has eyes like that, from what I read it was probably from temp fluctuations in the incubator. Not sure if the same can happen to cresties.

Thor's almost 9 months old and doesn't seem to have any ill effects from it

nothing constructive here, just tossing in that this crestie made me smile! She's ADORABLE! even will her silly little eyes. Gives her character =0)

The smaller eye does react to light, but it seems to do it kind of slowly. It doesn't seem to bother her so I guess I won't worry about it, I just wanted to make sure it wasn't a big deal or anything. Thanks everyone!