Good advice so far, but I prefer to use a product called Maxi-Guard. It is available from most vets ( it is a dog product).
www.addisonlabs.com/products/maxiguard-oral-cleansing-gel.php

Best of Luck

Buddy B

Hi :) I'm new to this site. I have a panther chameleon who I believe has mouth rot. I saw this thread and you guys seemed great and full of advice so... thought I'd try here. I'll be using the advice given on here previously and making a vet visit, but I had a few questions.  I know for a fact that my vet favors baytril... is that not the best? Also, what are some other symptoms of mouth rot? My lil guy has become very lethargic, doesn't eat much, and doesn't open his eyes much. I flush his eyes with eyewash because he has had some issues with them in the past, but lately he's simply keeping them shut for no apparent reason. He's very sluggish and doesn't want to eat anything. Lately when he sleeps at night he has been turining almost white. It scares me. I usually wake him up and hold him for a few minutes when I see this, and once his color changes to his usual blue I put him back and closer to the heat source. I don't know if I'm overreacting with the white thing, could just be him being relaxed sometimes the colors for his moods change, but it started recently. The first time I saw him white it really scared me.

I'm going to replace his UVB bulb (I usually do every 5 months, but I'm gonna do it early). Would adding a second UVB bulb for extra exposure help? I'll also add something for extra heat... trying to figure out what. It's hard to keep an enclosure hot when it's not glass. I currently have a ceramic heat emitter and a basking bulb on his enclosure. With that his cage is usually between 70 & 85 throughout it this time of year. We currently have cold weather, which doesn't make things any easier. I have a heat rope that's like my back up, and a thermostat I can hook it up to. I've never used those though. Are they totally safe to use? If I'm at work for an entire day and can't check up on him I need to know that the heat rope can't cause a fire, burn him, or simply get too hot. Have any of you used one before? I've attatched the heat rope to the back of the cage on the outside using foil tape. 

This is what I have: http://www.bigappleherp.com/Big-Apple-Flexible-Heat-Ropes , http://www.thatpetplace.com/hygrotherm-humidity-temperature-controller

When it comes to the baytril... I don't have the best experiences with my herp vets. So, far each one I've seen has cared and tried very hard to help as best as they can, some going completely out of the way trying to find answers, but they don't seem to know that much about dealing with chameleons. They seem to be playing a guessing game. I brought him to the vet not long ago knowing he was sick and we just thought it was his eyes bothering him again because that's been a recurring theme with him, but I noticed that this time was different and the vet didn't notice anything about his mouth or even look at it, I think if she had known what she was doing she probably would have caught it, but instead I'm here guessing, realized it on my own, and I'm hoping he lasts long enough for treatment. So, my point is... please give me some advice on which meds I should request depending on what kind of infection it is. The vets pretty much listen to what I tell and ask them because, like I said, they don't know too much themselves and don't want me to realize they don't know. If I went to my local vet and asked for dosages of a certain med for him they'd just give it to me right there and I'd just have to pay for that even without an appointment. I'll bring him for an appointment since he needs a culture done and then I can request certain medicine for him.

Thank you! :)

I would recommend adding a new question. This won't refresh to the top like a forum post; I only saw it because I subscribed to it when it was new.

That being said, I'm wondering about his nutrition.